制御性T細胞を介したシェーグレン症候群発症機序の解明

トップ›記事›制御性T細胞を介したシェーグレン症候群発症機序の解明

平成29年度 若手研究者学長表彰 疯狂体育,疯狂体育app下载報告

 

報告者

徳島大学医歯薬学研究部 口腔分子病態学分野 助教 山田安希子

 

研究タイトル

制御性T細胞を介したシェーグレン症候群発症機序の解明

 

研究経緯等

【研究グループ】

  • 徳島大学医歯薬学研究部 口腔分子病態学分野 山田安希子
  • 徳島大学医歯薬学研究部 口腔分子病態学分野 牛尾彩
  • 徳島大学医歯薬学研究部 口腔分子病態学分野 新垣理恵子
  • 徳島大学医歯薬学研究部 疾患病理学分野 常松貴明
  • 徳島大学医歯薬学研究部 口腔分子病態学分野 工藤保誠
  • 徳島大学医歯薬学研究部 口腔分子病態学分野 石丸直澄

 

【学術誌等への掲載状況】(最近5年以内のもの)

[欧文原書]

1)Pathological Analysis of Ocular Lesions in a Murine Model of Sjögren's Syndrome Ushio A, Arakaki R, Eguchi H, Hotta F, Yamada A, Kudo Y, Ishimaru N, International Journal of Molecular Sciences, 2017, 6, 18(6)(査読有)

2)Establishment and characterization of a clear cell odontogenic carcinoma cell line with EWSR1-ATF1 fusion gene, Kujiraoka S, Tsunematsu T, Sato Y, Yoshida M, Ishikawa A, Tohyama R, Tanaka M, Kobayashi Y, Kondo T, Ushio A, Otsuka K, Kurosawa M, Saito M, Yamada A, Arakaki R, Nagai H, Nikai H, Takeuchi K, Nagao T, Miyamoto Y, Ishimaru N, Kudo Y, Oral Oncology, 2017, 9, 46-55(査読有)

3)Human odontogenic epithelial cells derived from epithelial rests of Malassez possess stem cell properties, Tsunematsu T, Fujiwara N, Yoshida M, Takayama Y, Kujiraoka S, Qi G, Kitagawa M, Kondo T, Yamada A, Arakaki R, Miyauchi M, Ogawa I, Abiko Y, Nikawa H, Murakami S, Takata T, Ishimaru N, Kudo Y, Laboratory Investigation, 2016, 96(10), 1063-1075(査読有)

4)Analysis of the structure and function of EMRE in a yeast expression system, Yamamoto T, Yamagoshi R, Harada K, Kawano M, Minami N, Ido Y, Kuwahara K, Fujita A, Ozono M, Watanabe A, Yamada A, Terada H, Shinohara Y, Biochim Biophys Acta, 2016, 1857(6), 831-839(査読有)

5)Acceleration of tumor growth due to dysfunction in M1 macrophages and enhanced angiogenesis in an animal model of autoimmune disease, Kondo T, Tsunematsu T, Yamada A, Arakaki R, Saito M, Otsuka K, Kujiraoka S, Ushio A, Kurosawa M, Kudo Y, Ishimaru N, Laboratory Investigation, 2016, 96(4), 468-480(査読有)

6)Impaired expansion of regulatory T cells in a neonatal thymectomy-induced autoimmune mouse model, Yamada A, Ushio A, Arakaki R, Tsunematsu T, Kudo Y, Hayashi Y, Ishimaru N, American Journal of Pathology, 2015, 185(11), 2886-2897(査読有)

7)Neuroendocrine tumor in the mandible: a case report with imaging and histopathologic findings, Sugawara C, Takahashi A, Kawano F, Kudoh T, Yamada A, Ishimaru N, Hara K, Miyamoto Y, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, 2015, 119(1), e41-48(査読有)

8)Aromatase controls Sjögren syndrome-like lesions through monocyte chemotactic protein-1 in target organ and adipose tissue-associated macrophages, Iwasa A, Arakaki R, Honma N, Ushio A, Yamada A, Kondo T, Kurosawa E, Kujiraoka S, Tsunematsu T, Kudo Y, Tanaka E, Yoshimura N, Harada N, Hayashi Y, Ishimaru N, American Journal of Pathology, 2015, 185(1), 151-161(査読有)

9)Anti-inflammatory effects of rebamipide eyedrop administration on ocular lesions in a murine model of primary Sjögren's syndrome, Arakaki R, Eguchi H, Yamada A, Kudo Y, Iwasa A, Enkhmaa T, Hotta F, Mitamura-Aizawa S, Mitamura Y, Hayashi Y, Ishimaru N, PLoS One, 2014, 9(5), e98390(査読有)

10)A critical role for thymic stromal lymphopoietin in nickel-induced allergy in mice, Ashrin MN, Arakaki R, Yamada A, Kondo T, Kurosawa M, Kudo Y, Watanabe M, Ichikawa T, Hayashi Y, Ishimaru N, Journal of Immunology, 2014, 192(9), 4025-4031(査読有)

11)Gimap3 and Gimap5 cooperate to maintain T-cell numbers in the mouse, Yano K, Carter C, Yoshida N, Abe T, Yamada A, Nitta T, Ishimaru N, Takada K, Butcher GW, Takahama Y, European Journal of Immunology, 2014, 44(2), 561-572(査読有)

12)Induction of rapid T cell death and phagocytic activity by Fas-deficient lpr macrophages, Oura R, Arakaki R, Yamada A, Kudo Y, Tanaka E, Hayashi Y, Ishimaru N, Journal of Immunology, 2013, 190(2), 578-585(査読有)

13)Fas-independent T-cell apoptosis by dendritic cells controls autoimmune arthritis in MRL/lpr mice, Izawa T, Kondo T, Kurosawa M, Oura R, Matsumoto K, Tanaka E, Yamada A, Arakaki R, Kudo Y, Hayashi Y, Ishimaru N, PLoS One, 2012, 7(12), e48798(査読有)

14)CCR7 with S1P1 signaling through AP-1 for migration of Foxp3+ regulatory T-cells controls autoimmune exocrinopathy, Ishimaru N, Yamada A, Nitta T, Arakaki R, Lipp M, Takahama Y, Hayashi Y, American Journal of Pathology, 2012 , 180(1), 199-208(査読有)

[和文原書]

[欧文総説]

1)Dual Role of Fas/FasL-Mediated Signal in Peripheral Immune Tolerance, Yamada A, Arakaki R, Saito M, Kudo Y, Ishimaru N, Frontiers in Immunology, 2017, 5, 8, 403(査読有)

2)Unique Phenotypes and Functions of Follicular Helper T Cell and Regulatory T Cell in Sjögren's Syndrome. Saito M, Otsuka K, Ushio A, Yamada A, Arakaki R, Kudo Y, Ishimaru N, Current Rheumatology Reviews, 2017(査読有)