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研究実績

2012-2025

  1. Ventilation/Perfusion Mismatch in Pulmonary Vein Stenosis Secondary to Atrial Fibrillation Ablation, Bollos, L. A. C., Kasai, R., Otsuka, H., Otomi, Y., Yamaguchi, K., Matsuura, T., Otani, T., Bando, T., Ueki, Y., Matsuda, N., Takashi, S., Azane, S., Kunikane, Y., Takao, S., Yagi, S., Sata, M., Ikushima, H., Harada, M. Asia Oceania Journal of Nuclear Medicine and Biology, (), pp. -. 2024. doi: 10.22038/aojnmb.2024.79650.1561

  2. 11C-Methionine PET/CT in Cryptococcus Meningoencephalitis. Yoichi Otomi, MD, PhD, Natsumi Teshima, MD, Takayoshi Shinya, MD, PhD, Hideki Otsuka, MD, PhD, Masafumi Harada, MD, PhD, Clin Nucl Med 2024　DOI:10.1097/RLU.0000000000005593

  3. Quantitative evaluation of 67Ga-citrate scintigraphy in the management of nephritis. Matsuda, N., Otsuka, H., Kasai, R. et al. Sci Rep 14, 16313 (2024). https://doi.org/10.1038/s41598-024-66823-2 (https://rdcu.be/dNToi)

  4. 177Lu-DOTATATE Uptake in the Lungs of a Patient With COVID-19 Pneumonia. Matsushita T, Otomi Y, Okada N, Kawanaka T, Otsuka H. Clin Nucl Med. 2024 Jul 4. doi: 10.1097/RLU.0000000000005324. Epub ahead of print. PMID: 38968595.

  5. Nuclear medicine practice in Japan: a report of the ninth nationwide survey in 2022. Atsutaka Okizaki, Yoshihiro Nishiyama, Yoshitaka Inui, Hideki Otsuka, Kentaro Takanami, Masatoyo Nakajo, Koya Nakatani, Munenobu Nogami, Kenji Hirata, Yukito Maeda, Mana Yoshimura & Hiroshi Wakabayashi. Annals of Nuclear Medicine, Published: 29 February 2024. https://rdcu.be/dz1gZ

  6. Combined visual and quantitative assessment of somatostatin receptor scintigraphy for staging and restaging of neuroendocrine tumors. Yuya Ueki, Hideki Otsuka, Tamaki Otani, Ryosuke Kasai, Youichi Otomi, Daiki Ikemitsu, Shota Azane, Yamato Kunikane, Takanori Bandoh, Nnoritake Matsuda, Yasuyuki Okada, Tetsuji Takayama and Masafumi Harada. Japanese Journal of Radiology, Vol.42, No.2, 2024.

  7. Noise Reduction Using Singular Value Decomposition with Jensen–Shannon Divergence for Coronary Computed Tomography Angiography. Ryosuke Kasai and Hideki Otsuka. 2023. Diagnostics 13, no. 6: 1111. https://doi.org/10.3390/diagnostics13061111

  8. 11C-Methionine PET/CT and 18F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma. Yuka Hiroshima , Yoichi Otomi , Takayoshi Shinya, Hideki Otsuka , Masafumi Harada. Mol Imaging Radionucl Ther. 2023 Feb 23;32(1):62-64. 

  9. New quantitative indices of cardiac amyloidosis with 99mTc-pyrophosphate scintigraphy. Noritake Matsuda, Hideki Otsuka, Tamaki Otani, Shota Azane, Yamato Kunikane, Yoichi Otomi, Yuya Ueki, Masahiro Kubota, Masafumi Amano, Shusuke Yagi, Masataka Sata and Masafumi Harada. Japanese Journal of Radiology, Nov. 30, 2022. ISBN: 1867-108X. DOI: https://doi.org/10.1007/s11604-022-01364-0, URL: https://rdcu.be/c0Lji

  10. 18F-FDG PET/CT Showing Rare Mediastinal Growing Teratoma Syndrome Following Chemotherapy. Mihoko Sasahara, Takashi Abe , Yoichi Otomi , Yumi Abe , Hiroaki Toba , Takayoshi Shinya , Hideki Otsuka , Masafumi Harada. Mol Imaging Radionucl Ther. 2022 Oct 19;31(3):239-241. 

  11. Multicystic Biliary Hamartoma With Xanthogranulomatous Inflammation on 18F-FDG PET/CT. Nahomi Shono, Yoichi Otomi, Hideki Otsuka, Takayoshi Shinya, Masafumi Harada.
    Clinical Nuclear Medicine, 2022.

  12. Increased physiological [18F]FDG uptake in the liver and blood pool among patients with impaired renal function. Yoichi Otomi, Yuta Arai, Maki Otomo, Saho Irahara, Kaori Terazawa, Michiko Kubo, Takashi Abe, Takayoshi Shinya, Hideki Otsuka, Masafumi Harada. Nucl Med Rev Cent East Eur. 2022;25(2):95-100.  Epub 2022 Jul 18.

  13. Increased 18F-FDG Uptake in the Axillary Lymph Nodes of the Vaccinated Side Associated with COVID-19 Vaccination. Yoichi Otomi, Saho Irahara, Hiroaki Inoue, Takayoshi Shinya, Hideki Otsuka, Masafumi Harada. Mol Imaging Radionucl Ther. 2022 Jun 27;31(2):169-171. 

  14. The Utility of a Combination of 99mTc-MIBI Washout Imaging and Cardiac Magnetic Resonance Imaging in the Evaluation of Cardiomyopathy.
    Moriaki Yamanaka, Shoichiro Takao, Hideki Otsuka, Yoichi Otomi, Saho Irahara, Yamato Kunikane, Satoru Takashi, Airi Yamamoto, Masataka Sata, Masafumi Harada 
    Annals of Nuclear Cardiology [Advance publication] Released: June 25, 2021  https://doi.org/10.17996/anc.21-00124

  15. Effect of different examination conditions on image quality and quantitative value of amyloid positron emission tomography using 18 F- flutemetamol.   
    Tamaki Otani, Hideki Otsuka, Kou Matsushita, Yoichi Otomi, Yamato Kunikane, Shota Azane, Masafumi Amano, Masafumi Harada, Hirokazu Miyoshi　
    Ann Nucl Med. 2021 May 27. doi: 10.1007/s12149-021-01634-3. Online ahead of print. 35; 1004-1014. 2021

  16. A new quantitative index in the diagnosis of Parkinson syndrome by dopamine transporter single-photon emission computed tomography. 
    Ryota Bando, Hideki Otsuka, Tamaki Otani, Noritake Matsuda, Shota Azane, Yamato Kunikane, Yoichi Otomi, Wataru Sako, Yuishin Izumi, Masafumi Harada.  
    Ann Nucl Med 2021;35(4):504-513.

  17. A reduced liver 18F-FDG uptake may be related to hypoalbuminemia in patients with malnutrition. Yoichi Otomi, Hideki Otsuka, Kaori Terazawa, Mihoko Kondo, Yuta Arai, Moriaki Yamanaka, Maki Otomo, Takashi Abe, Takayoshi Shinya, Masafumi Harada. Ann Nucl Med. 2019 Sep;33(9):689-696. doi: 10.1007/s12149-019-01377-2. Epub 2019 Jun 14.

  18. Diagnosis of recurrence and follow-up using FDG-PET/CT for postoperative non-small-cell lung cancer patients. Toba H, Kawakita N, Takashima M, Matsumoto D, Takizawa H, Otsuka H, Tangoku A. Gen Thorac Cardiovasc Surg. 2021 Feb;69(2):311-317.

  19. Use of a Prognostic Risk Score That Aggregates the FDG-PET/CT SUVmax, Tumor Size, and Histologic Group for Predicting the Prognosis of pStage I Lung Adenocarcinoma.
    Kawakita N,  Toba H, Kawakami Y, Takizawa H, Bando Y, Otuska H, Matsumoto D, Takashima M, Tsuboi M, Yoshida M, Kondo K, Tangoku A.
    Int J Clin Oncol. 2020 Jun;25(6):1079-1089

  20. Differences in cerebellar perfusion between Parkinson's disease and multiple system atrophy.
    Murakami N, Sako W, Haji S, Furukawa T, Otomi Y, Otsuka H, Izumi Y, Harada M, Kaji R.
    J Neurol Sci. 2020 Feb 15;409:

  21. Preliminary clinical assessment of dynamic (18)F-fluorodeoxyglucose positron emission　tomography/computed tomography for evaluating lymph node metastasis in patients with lung   cancer: a prospective study.
    Shinya T, Otomi Y, Kubo M, Kinoshita M, Takechi K, Uyama N, Yamanaka M, Terazawa K, Toba H, Bando Y, Otsuka H, Harada M.
    Ann Nucl Med. 2019 Jun;33(6):414-423.  

  22. Appropriate echo time selection for quantitative susceptibility mapping.
    Kanazawa Y,  Matsumoto Y, Harada M, Hayashi H, Matsuda T, Otsuka H.   
    Rad Phys Tech. 2019; 12(2), 185-193.

  23. Proposal of a new method to prove that unnecessary information is not drawn on the image using statistical analysis. 
    Isayama T,Nishihara S, Otsuka H.
    Rad Phys Tech. 2019;12(2), 156-160. 

  24. Non?invasive monitoring of cisplatin and erlotinib efficacy against lung cancer in orthotopic SCID mouse models by small animal FDG?PET/CT and CT.
    Otani T, Kondo K, Takizawa H, Kajiura K, Fujino H, Otsuka H, Miyoshi H.
    Oncol Rep. 2019; 41(1):447-454.  

  25. Potential Utility of 123I-MIBG Scintigraphy as a Predictor of Falls in Parkinson's Disease.
    Murakami N, Sako W, Haji S, Furukawa T, Otomi Y, Otsuka H, Izumi Y, Harada M, Kaji R.
    Front Neurol. 2019 Apr 12;10:376.

  26. Clinical Imaging Technology and the Diagnosis in Patient-centered Interdisciplinary Care.
    Otsuka H.　J Med Invest. 2019;66(1.2):31-34.

  27. The diagnostic ability of SPECT/CT fusion imaging for gastrointestinal bleeding: a retrospective  study.
    Otomi Y, Otsuka H, Terazawa K, Yamanaka M, Obama Y, Arase M, Otomo M, Irahara S, Kubo M, Uyama N, Abe T, Harada M.
    BMC Gastroenterol. 2018 Dec 10;18(1):183.

  28. Comparison Between Prone and Upright Imaging of the Inferior Wall Using 201TlCl Myocardial Perfusion SPECT.
    Nakaya K, Onoguchi M, Nishimura Y, Kiso K, Otsuka H, Nouno Y, Shibutani T, Yasuda E.
    J Nucl Med Technol. 2017 Dec;45(4):304-308.

  29. Criteria for the addition of prone imaging to myocardial perfusion single-photon emission computed tomography for inferior wall.
    Nakaya K, Onoguchi M, Nishimura Y, Kiso K, Otsuka H, Nouno Y, Shibutani T, Yasuda E.
    Nucl Med Commun. 2017 Sep;38(9):748-755.

  30. The physiological accumulation of FDG in the muscles in relation to the side of intravenous administration. Yoichi Otomi , Takayoshi Shinya , Naoto Uyama , Yuta Arai , Kanako Miyamoto , Katsuya Takechi , Michiko Kubo, Hideki Otsuka, Masafumi Harada 

    Jpn J Radiol. 2017 Feb;35(2):53-60. doi: 10.1007/s11604-016-0597-4. Epub 2016 Nov 3.

  31. The utility of the combination of a SPECT study with [123I]-FP-CIT of dopamine transporters and [123I]-MIBG myocardial scintigraphy in differentiating Parkinson disease from other degenerative parkinsonian syndromes.
    Uyama N, Otsuka H, Shinya T, Otomi Y, Harada M, Sako W, Izumi Y, Kaji R, Watanabe Y, Takashi S, Kunikane Y.
    Nucl Med Commun. 2017 Jun;38(6):487-492

  32. Multimodal Cardiovascular Imaging of Cardiac Tumors
    Ayaka Takahashi MD , Hideki Otsuka MD, PhD and Masafumi Harada MD, PhD
    Annals of Nuclear Cardiology Vol. 2 No. 1 61-67, 2016

  33. The physiological accumulation of FDG in the muscles in relation to the side of intravenous administration.
    Otomi Y, Shinya T, Uyama N, Arai Y, Miyamoto K, Takechi K, Kubo M, Otsuka H, Harada M.
    Jpn J Radiol. 2016 Nov 3. [Epub ahead of print]

  34. Increased (18)F-fluorodeoxyglucose accumulation in bilateral adrenal glands of the patients suffering from vasovagal reaction due to blood vessel puncture.
    Otomi Y, Shinya T, Otsuka H, Terazawa K, Irahara S, Nagase S, Takahashi A, Kubo M, Harada M.
    Ann Nucl Med. 2016 Aug;30(7):501-5.

  35. 肺癌の経過観察におけるFDG-PET/CTの役割とPETに関する新技術  大塚秀樹 Annual Review 呼吸器 2016 :123-131

  36. Tumor growth-inhibitory effect of an angiotensin-converting enzyme inhibitor (captopril) in a lung cancer xenograft model analyzed using 18F-FDG-PET/CT.
    Nakaya K, Otsuka H, Kondo K, Otani T, Nagata M.
    Nucl Med Commun. 2016 Feb;37(2):139-46.

  37. Utility of respiratory-gated small-animal PET/CT in the chronologic evaluation of an orthotopic lung cancer transplantation mouse model. Otani T, Otsuka H, Kondo K, Takizawa H, Nagata M, Kishida M, Miyoshi H. Radiol Phys Technol. 2015 Jul;8(2):266-77. doi: 10.1007/s12194-015-0316-3. Epub 2015 Apr 29.

  38. Usefulness of the SNR Using the Subtraction Method and Image Visibility Using the Howlett Chart Method in X-Ray Fluoroscopic System.
    Nishihara S, Yamashita Y, Kawai N, Otsuka H.
    Open Journal of Medical Imaging. 2014;4:49-56. http://dx.doi.org/10.4236/ojmi.2014.42007

  39. 虚血性心疾患の診断(5) 核医学検査 大塚 秀樹 日本放射線技術学会雑誌 Nuclear cardiology in ischemic heart disease. Otsuka H. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2014 Jan;70(1):102-11.

  40. Non-invasive monitoring of anticancer effects of cisplatin on lung cancer in an orthotopic SCID mouse model using [18F] FDG PET-CT.
    Mokhtar M, Kondo K, Takizawa H, Ohtani T, Otsuka H, Kubo H, Kajiura K, Nakagawa Y, Kawakami Y, Yoshida M, Fujino H, Sakiyama S, Tangoku A.
    Oncol Rep. 2014 Mar 5.

  41. Comparing the performance of visual estimation and standard uptake value of F-18 fluorodeoxyglucose positron emission tomography/computed tomography for detecting malignancy in pancreatic tumors other than invasive ductal carcinoma.
    Otomi Y, Otsuka H, Terazawa K, Nose H, Kubo M, Matsuzaki K, Ikushima H, Bando Y, Harada M.
    J Med Invest. 2014;61(1-2):171-9.

  42. The physiological uptake pattern of (18)F-FDG in the left ventricular myocardium of patients without heart disease.
    Nose H, Otsuka H, Otomi Y, Terazawa K, Takao S, Iwamoto S, Iwase T, Yamada H, Sata M, Harada M.
    J Med Invest. 2014;61(1-2):53-8.

  43. Correlations between F-18 FDG PET/CT and pathological findings in soft tissue lesions.
    Nose H, Otsuka H, Otomi Y, Terazawa K, Takao S, Iwamoto S, Harada M.
    J Med Invest. 2013;60(3-4):184-90.

  44. The impact of self-shielded cyclotron operation on small-animal PET/CT equipment installed nearby, on the floor just above. Kubo H, Otani T, Otsuka H, Harada M.  J Med Invest. 2014;61(1-2):46-52.

  45. Visual and semi-quantitative assessment of brain tumors using (201)Tl-SPECT. 
    Nose A, Otsuka H, Nose H, Otomi Y, Terazawa K, Harada M.
    J Med Invest. 2013;60(1-2):121-6.

  46. 18F-fluorodeoxyglucose positron emission tomography/computed tomography and the relationship between fluorodeoxyglucose uptake and the expression of hypoxia-inducible factor-1α, glucose transporter-1 and vascular endothelial growth factor in thymic epithelial tumours. 
    Toba H, Kondo K, Sadohara Y, Otsuka H, Morimoto M, Kajiura K, Nakagawa Y, Yoshida M, Kawakami Y, Takizawa H, Kenzaki K, Sakiyama S, Bando Y, Tangoku A.
    Eur J Cardiothorac Surg. 2013 Aug;44(2)

  47. Preliminary observation of dynamic changes in alcohol concentration in the human brain with proton magnetic resonance spectroscopy on a 3T MR instrument. 
    Kubo H, Harada M, Sakama M, Matsuda T, Otsuka H.
    Magn Reson Med Sci. 2013;12(3):235-40. Epub 2013 Jul 12.

  48. (18)F-2-fluoro-2-deoxyglucose uptake in or adjacent to blood vessel walls. 
    Otomi Y, Otsuka H, Terazawa K, Nose H, Kubo M, Yoneda K, Kitsukawa K, Harada M.
    J Med Invest. 2013;60(1-2):15-20. Review.

  49. The utility of FDG-PET in the diagnosis of thymic epithelial tumors. 
    Otsuka H. J Med Invest. 2012;59(3-4):225-34. Review.

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